I'm just going to put this out there..
I know a lot of people are saying vehicles/explosions/whatever are causing their PhysX3 crash. I'm getting the exact same crash (started happening with the last patch) and have exhibited the same issue with explosions etc, but it's far more random than just explosions in my experience. I crash when sweeping my mouse side to side while out in the wilderness - away from any vehicles or explosions. Happens after the same 5-20 minutes. I'll start posting minidumps if that helps. (And no, I have not been on dev builds)