@SuicideKing: curiously, I can't remember female enemies in Tomb Raider (the new one), Mass Effect (1&2), Mirror's Edge (besides the boss that you don't get to kill), Portal1/2 (no, GLADoS is an AI), nor HALO (I only played 1 and part of 2, so there is that).

OTOH, yeah, nobody has problems shooting... well, anyone in Planetside 2 (can you even tell them apart to begin with?). No idea why, but personally while in somewhere in my mind is a thought stating "yeah, there probably are female players", I perceive the player base to be male regardless of character model (problem increased because I regularly play with female characters in games that allow me to). So in the end even if I could tell them apart under the heat of the battle I would probably care not because I just assume they are male players. That's what I perceive. Besides, most of the time you're too busy trying to kill the other and not die to pick your targets apart other than threat level and Friendly or Foe.

That, and I try to tell myself that, ultimately, we are all players and that what matters is how good we are at the game, how we act towards others (not being an ass is good), regardless of sex, age, color, political stance, etc...