I have encountered this problem with a bunch of items (sardines, chemlight, ..) on the second floor of a building. They were right next to a shelf and I could see them in my vicinity-tab but I wasn't able to pick them up. Aiming the dot and pressing F / mouse-wheel didn't help either.

BUT I was able to pick up the sardines by opening them with an axe, which put them into my inventory.

Hi,
is this an issue with items e.g. on top of a wardrobe, which could be far from reach?
Providing a screenshot of such a bugged item with the position of the character visible would be quite beneficial.
Thank you,
Andy

It's exactly as Hollisbrown said. It's exactly like that.

But once i could exit the building, go back in and then be able to take at least one thing.

It's kinda hard to take a screenshot when it's not visual but mechanical :P

The thing is, it doesnt say far from reach, you can see it, stand very next to it, even press F and it does nothing.

Thanks for specifying.
A screenshot would still help as the issue can be item or building related, please feel free to provide some if you encounter the issue again.
We will look into the problem and let you know.
Regards,
Andy

Well it happens in random buildings. :P

Could this be a similar issue to the old "rubber banding" geometry issue caused by the server and client thinking the player are in different places?

In other words, your client shows you hovering over the item you want to pick up, but the server doesn't think you're there, so it doesn't let you take it. Run out of the building and vault or something to get the server to rediscover where you are, go back in and voila you can pick it up.

Just a theory.

I actually might have something to do with that, because one time yesterday i couldnt pick up this epi pen, then i just did a 360 with my mouse inside the building and i could take it .. Then on another item .. it didnt work at all :P

A clanmember of mine has found a workaround for this problem. If the inventoryscreen is opened and you can not pick up the item, just drag and drop it out of the inventory screen (just to the left). It is necessary that you put it outside the inventory screen. Drag and Drop in the inventory screen won't help. After you did it you can pick up the item like nothing is wrong.

it is definitely tied to the desync/geometry thing

Musicman, that's the easiest workaround I've seen so far. If it is indeed a positioning issue, something about the dragging and dropping must force the server to recalculate the item's position relative to your character's position in the client.

yeah i found the same workaround as Musicman, this helps on all stuff. Another bug in the new 0.50 is many stuff is half or complete in the ground of the floor and not visible.

(apartment building) and (green orange wood house with 2 rooms)
http://cloud-4.steampowered.com/ugc/36353839570642463/AA727DB8EA50B405A53740E573481141A1A4A9E3/