Titan MPRL Missiles are -~*MaGiC*~- right now, as they appear to have been treated by Twilight Sparkle with a "I Home on everything even if I can´t see it and without having even locked on." spell.
They home on any target that has been selected (square box, no diamond). You can look in the opposite direction, launch the missile, and it will turn around 180° and fly into the target.
You can even teleport the target away from the missile right before it hits, and it will attempt to turn around towards the target and strike it again until it runs out of fuel.