When ever I switch from say my gun to a ax or anything really to kill a zombie up close, I have to mash my hot keys about 50 times before my player responds and pulls out my ax or switch to a different weapon or a can of soda. It doesn't matter what I switch to, most of the time "usually closer to cities" I have to press the buttons a lot, only them buttons from 1 to 0, moment is fine.
Also jumping (pressing V) will not respond sometimes until you put your weapon away or bring it out.