I have tried many different aspects to recreate this but it is completely random.
I have tried:
Every configuration of in game setting changes (Video settings drastically reduced) Etc..!
Setting Processor Affinity (so only 1 Physical Processor is utilized Core 0 & 1)
Complete game Uninstall/Reinstall
Disabling everything possible (Do Not Run Antivirus)
Disabling one of my 2 Monitors
Ive monitored my System temperatures to ensure its not getting over 70C
Probably a lot more that I am forgetting as of this moment