I've only tried this with the Gunter, not sure if affects other cars. If you come to a car that has been spawned, and remove the tires/move the tires to different spots on the car, get in/out of the car seats, eventually your character will get into a bugged state. You will not have the action option to remove tires, character will not be able to throw items, character when carrying a tire in hands will be able to move at regular jogging speed (not the normal walking only speed for heavy items like tires and car doors, barrels etc).
I'm not sure exactly what is the cause but it happens pretty consistently if I swap a couple tires (remove using Hold F then re-attach to different location) and get in and out of the car a few times, then my character gets into the bugged state. I have to relog or character is not able to throw any items.