When I'm in big cities the games will freeze for 3-5 seconds and after that the fps drops, the texture stops rendering(if I'm in a house i can see through walls, if I'm outside all the buildings have the low poly textures, the one you see when looking at a town from 1km) and the gpu seems to go idle.
Sometimes alt tabbing wil fix the issue but the only reliable way to fix it is by changing the rendering resolution to another value.

PC specs:
CPU: AMD Athlon 64 X2 5600+ @ 2.8Ghz
MB: ASRock 960GC-GS FX
Ram: 2 GB DDR2 @ 800Mhz
GPU: GeForce 8600 GT 512MB
HDD: Samsung 320GB 7200rpm
OS: Windows 10 32bits
Nvidia driver v341.74

launch options: -nosplash -noPause
But if i remember i tried without any launch option and i got the same problem.