Hello,
I have noticed that if you have a gun or melee weapon in your inventory, when you go to use it, it removes it from the inventory system.
This issue with this is if you're looting, you can fill your inventory or block if from being placed back into your inventory. Players can unintentionally drop it or have the item disappear.
1.) Loot up so that your inventory is 100% full and place the weapon or item that can be placed in hand into item bar.
2.) Pull item out (example, pistol)
3.) Find another item to place in your inventory to block the 4 slots of the pistol.
4.) Pick up a can to drink, or hit the hotkey on the item bar to "place it back" in your inventory. The item may end up on the ground without the users knowledge. In houses, items may disappear or be placed at one of the doorsteps.
I understand that taking item out of inventory to place in hand maybe intentional by design, but this could be frustrating to new and veteran players when they lose a valuable item.