Persistence causes servers to have barely any loot while other places have a freakish amount of loot and helicopter crash sites won't appear, but loot will.
With persistence enabled hotspot places never re spawn loot because the loot won't respawn on restart (military buildings, police stations, firestations).
Not only this, it means that helicopter crash sites will not show up unless you go to the few servers who say they have it disabled.
Server admins who wish to have items kept in over restarts should have to chose if they want to opt-in to it, as having persistence disabled has more advantages over having it enabled.