Agomir is chemically-modified double-strand miRNA mimics which can mimic mature endogenous miRNAs after transfection into cells. They can up-regulate the endogenous miRNA activity by utilizing the natural miRNA machinery. Creative Biogene’s microUP™ [[ https://www.creative-biogene.com/Services/microUP-miRNA-Agomir.html | miRNA agomir ]] is designed to mimic mature miRNAs, and chemically modified to increase their stability and activity. They are recommended for miRNA functional in vitro and in vivo studies.