Compared with traditional hybridoma technology, mRNA display technology has outstanding advantages in cycle time, screening scope, cost and expense. The process of mRNA display screening library is simple and efficient, which can obtain antibodies with strong affinity in a short time. CD BioSciences has devoted itself to the research of antibody field for many years, accumulated rich experience in antibody discovery, and can provide customers with multi type antibody discovery services based on [[ https://www.aspiregene.com/mrna-display-based-antibody-discovery.html | mRNA display-based antibody discovery services ]].
mRNA Display for Antibody Discovery
mRNA display technology is to use genetic engineering technology to synthesize or extract antibody genes and transcribe them into mRNA in vitro, connect the mRNA with the antibody obtained in the process of in vitro translation through puromycin, and then reverse transcribe to form a ternary complex and combine it with the target protein, complete the screening of antibody under mRNA display, and obtain high affinity and high specificity target antibody through multiple rounds of elutriation. Based on mRNA display technology, it can realize the discovery of many kinds of antibodies, including mouse monoclonal antibody, rabbit monoclonal antibody, chicken monoclonal antibody and all human monoclonal antibody.